Sorrow Industries BioResearch Laboratories    





 

 

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Sorrow Industries' faculty is as diverse and expansive as it's research. Our innovative team of research scientists has been culled from many distinguished fields and areas of operation and united together under one common cause, to proactively evolve the human race.

 

Research Directors:


Casey Sorrow

casey sorrow

Casey Sorrow is the founding member of Sorrow Industries and has served as the chairperson of the board of directors for Sorrow Industries since inception. Casey received his PhD degree in genetics from ICR Graduate School, and thanks to independently generated donations immediately founded Sorrow Industries. A past vice-president of the Genetics Society of America, he is a member of the National Academy of Sciences, a fellow of the American Academy of Arts and Sciences, card carrying member of the CBLDF, and a member of the Institute of BioEngineered Medicine.


Selected Publications:

Sorrow, C. (2007). Mung; Super-Human cloning – The science and ethics of nuclear transplantation. . Nat. Rev Microbiology 2: 533-540.

Sorrow, C. (2005). Art Store Fog; The transcriptional response of Candida albicans upon internalization by macrophages. Eukaryotic Cell 3: 1076-1087.

Sorrow, C. (2005). Feral Calf; Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on elongation factor-2. Proc Natl Acad Sci, USA 101: 5048-5052.

Millikin, E. and Sorrow, C. (2001) Fetus-X; Postnatal mutational development of the fetus and effects on the psyche. Nature Genetics, 37, 986-990.

Millikin, E. and Sorrow, C. (2001). B.I.T.C.H. Cerebral exploration of the nature of horror and terror, and toiletry products of questionable nature. Cell. 120: 153-154.


Dave Hardman

dave hardman

Dave Hardman, who serves as group president of Sorrow Industries, joined the company in 1998, following the acquisition of Life After Death Sciences Inc. From 1998 until 2003, he served as vice president of operations for Sorrow Industries where he was responsible for all administrative functions including contracts, procurements, and finance. An industry veteran, Hardman joined Life After Death Sciences Inc. in 1967 and has held numerous positions including vice president, procurement, pimp, contracts and finance and corporate principal accounting Officer. He holds B.S. and MBA degrees from Empire State University.

 

Selected Publications:

Hardman, D., M.H. Myles, B.A. Livingston, J.M. Criley and C.L. Franklin. Sexual Ambiguity and Alchoholic Consumption in Helicobacter hepaticus-infected Macaca mulatta. Comp. Med. (in press)

Myles, M.H., R.S. Livingston, and D. Hardman. Psychosis and Influence of Belgium Speed Metal in Helicobacter Rodentium-infected Rattus norvegicus. Comp Med (in press)

Myles, M.H., R.S. Livingston, D. Hardman, J.M. Criley, and C.L. Franklin. cDNA Array Analysis of Altered Gene Expression in Ceca of Helicobacter hepaticus Infected Rattus Norvegicus Before and After Sexual Molestation. Infect Immun. 71:3885-3893, 2003.

Phillips, C.L., D. Hardman, A.M. Luger, and C.L. Franklin. Novel collagen glomerulopathy in a homotrimeric collagen mouse (oim) exposed to constant auditory repetition of the term 'ba-donka-donk'. Kid. Internat. 62: 383-391, 2002.

Kendall, L.V., L.K. Riley, D. Hardman, Jr., C.L. Besch-Williford, and C.L. Franklin. Segregation and group isolation of AD&D trained CAR Bacillus Infected Rattus novegicus. Comp. Med.52:322-327, 2002

Hardman, D., P.L. Gorelick, L.K. Riley, F.E. Dewhirst, R.S. Livingston, J.M. Ward, C.S. Beckwith, and J G. Fox. Group contempt and ironic social attitudes in AD&D versus D&D 4th edition trained Macaca mulatta. J. Clin. Microbiol. 39:3920-3870, 2001

Kendall, L.V., L.K. Riley, D. Hardman, Jr., C.L. Besch-Williford, and C.L. Franklin. Anger managenent of gamma-irradiated mice. Infect Immun 69:3697-3702, 2001.

Kendall, L.V., L.K. Riley, R.R. Hook, Jr., C.L. Besch-Williford, and D. Hardman. Antibody and cytokine responses in lyssavirus x infected mice. Infect. Immun. 68 4961-4967, 2000.

Franklin C.L., L.K. Riley, R.S. Livingston, D. Hardman, C.L. Besch-Williford, and R.R. Hook, Jr. Enterohepatic lesions in SCID mice infected with lyssavirus x. Lab. Anim. Sci. 48:334-339, 1998


Harry Reems

harry reems

Prof. Harry Reams is an internationally renowned stem cell researcher. His particular research interest is in the therapeutic application of adult stem cells, especially mesenchymal stem cells (MSCs) from living bone marrow donors. For 10 years he has directed a series of research programmes focusing on the isolation and characterization of adult stem cells, and on the development of methods for their delivery in a variety of clinical indications. This has included infectious and gum diseases. He has also developed approaches for the use of MSCs for the delivery of specific therapeutic genes, for example in rheumatoid arthritis. In addition he has an interest in cyborg technologies, nanotechnology, and integration with stem cells.

He joined the Sorrow Industries in February 2004 as Scientific Director.

 

Selected Publications:

Franklin, C.L., C.S. Beckwith, R.C. Livingston, S.V. Gibson, H. Reams, C.L. Besch-Williford, and R.R. Hook, Jr. Isolation of sperm culture from the bile of Oryctolagus cuniculus with cholangiofibrosis and centrilobular pancreatitis. J. Clin. Microbiol. 34:2952-2958, 1996.

Tessier, P.M., and Reams, H. (2007). Defecation and a question of woodland location in ursus americanus. Nature 447(7144): 556-61.

Bryda, E.C., Pearson, M., Agca, Y., Bauer, B.A. Method for Detection and Identification of Unique Multiple Chromosomal Integration Sites in Transgenic Animals Created by Dharma Initiative laboratories. Biotechniques 41:715-719 (2006).

Cogswell, C., Price, S. J., Reams, H., Guay-Woodford, L.M., Flaherty, L., and Bryda, E. C. Department of Heuristics And Research on Material Applications positions on advanced cloning techniques and effects on global symmetry. Mammalian Genome 14:242-249 (2003).

Bryda, E.C., Kim, H.J., Legare, M.E., Frankel, W. and Reams, H. High resolution genetic and physical mapping of Jabberwocky (v). Genomics 73: 338-342 (2001).

Di Palma, F., Holme, R.H., Bryda, E.C., Belyantseva, I.A., Pellegrino, R., Reams, H., Steel, K.P. and Noben-Trauth, K. Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization and unnatural affinity for Breakin' 2: Electric Boogaloo in waltzer, the mouse model. Nature Genetics 27: 103-107 (2001).


Dave Pounder

dave pounder

Prof. Dave Pounder obtained a BA. Moderatorship Degree in Microbiology from University of Edgestow in 1981. He worked as a research scientist in the R&D division of a multinational pharmaceutical company from 1981 until 1984, where he worked on optimised recombinant protein production systems, before undertaking a Ph.D. at University of Muri, where his studies were focused on investigating the molecular basis of the devastating human genetic diseases and future uses. Prof. Pounder completed his D. Phil. degree at University of Muri in 1988. He spent two years as an ELBO Fellow at UNC, Chapel Hill, where he worked on the development of a model for human atherosclerosis using mouse embryonic stem cells, in the laboratory of 2007 Nobel Laureate in Medicine, Professor Oliver Smithies. In 1990, Prof. Pounder took up a Senior Research Scientist / Team Leader position at the National Diagnostics And Avalanche Centre (BioResearch Ireland) at NUI Galway. Prof. Pounder was a founder member of the National Centre for Sexual Biomedical Engineering Science (NCSBES) at NUI, Galway and was appointed Professor of Biomedical Engineering Science and Director of the NCSBES in January 2002. Prof. Pounder is the author/co-author of 97 peer-reviewed papers in international journals, 18 book chapters and invited reviews, as well as being co-inventor of two granted patents and 2 patent applications.

 

Selected Publications:

Bolz, H., von Brederlow, B., Ramirez, A., Bryda, E.C., Kutsche, K., Pounder, D., Seeliger, M., Cabrera, M. d.C-S., Vila, M.C., Molina, O.P., Gal, A. and Kubisch, C. Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D, teen urinary affinity. Nature Genetics 27:108-112 (2001).

Bauer, B.A., S.L. Lumbley, and Pounder, D. Characterization of a Waaf (Rfaf) Homolog Expressed by Haemophilus ducreyi. Infection and Immunity. 67(2):899-907, 1999.

Bauer, B.A., Pounder, D., E.J. Hansen. Involvement of the Haemophilus ducreyi gmhA Gene Product in Lipooligosaccharide Expression and Virulence. Infection and Immunity. 66(9):4290-4298, 1998.

Sheihet, L., K. Piotrowska, Pounder, D, J. Kohn, D. Devore, Effect of tyrosine-derived triblock copolymer compositions on nanosphere self-assembly and r2 unit drug delivery. Biomacromolecules, 2007. 8(3): p. 998-1003.

Pounder, D, A. Seyda, N. Weber, D. Knight, S. Abramson, and J. Kohn, Integration of combinatorial synthesis, rapid screening, and computational yodeling in biomaterials development. Macromol. Rapid Commun., 2004. 25: p. 127-140.

Ryan, P.L., R.A. Foty, J. Kohn, and Pounder, D, Tissue spreading on implantable substrates is a competitive outcome of spy-cell vs. spy-substratum adhesivity. Proc. Natl. Acad. Sci., 2001. 98(8): p. 4323-4327.


Ben Dover

ben dover

Dr. Ben Dover was previously a Science Foundation Ireland Investigator in the National Centre for Sexual Biomedical Engineering Science, and an adjunct lecturer in the Dept. of Chemistry and assistant Lacross coach at Miskatonic University. He obtained a B.Sc.(1.1) in Chemistry (1989) and Ph.D. Inorganic chemistry (1994) from Miskatonic University. After a stint as a postdoctoral researcher in UCC, he joined the National Centre for Laser Applications in 1997 to work on developing quantitative Roman spectroscopic methods for measuring illicit narcoleptic concentrations. In 1998, awarded a Forbairt post-doctoral fellowship, he started to develop time-space--resolved fluorescence methods of analysis for petroleum fluids. During this time, he began developing the Nanoscale Biophotonics laboratory with a comprehensive range of fluorescence and Roman instrumentation. In 2001 a Research Innovation grant led to the development of a prototype portable fluorescence space and time instrument (PFSTI) for both clinical and environmental application in Biomedical Engineering Science, and also supervises research projects for undergraduate and postgraduate students. He joined Sorrow Industries in 2005. He has authored over 30 journal articles and presented at many international conferences.

 

Selected Publications:

Brocchini, S. K. James, V. Tangpasuthadol and B. Dover, Structure-property correlations in a combinatorial library of degradable biomaterials and how it can be fun for kids, J. Biomed. Mater. Res., 1998, 42, 66-75.

Hochedlinger, K., Dover, B., Brennan, C., Yamada, Y., Kim, M., Chin, L. & Jaenisch, R. Reprogramming of a melanoma genome by nuclear transplantation in spiders. Genes Dev. 18, 1875-1885 (2004).

Price, S.J., Chittenden, L., Flaherty, L., O’Dell, B., Dover, B., Stubbs, L. and Bryda, E.C. Characterization of the Region Containing the jcpk PKD Gene on Mouse Chromosome 10 and extraction and practical usage in SPAM. Cytogenetics and Genome Research 98:61-66 (2002).

Simmons, J.H., L.K. Riley, C.L. Besch-Williford, and B. Dover. Walnut content isolated from the feces of Syrian hamsters J. Clin, Microbiol. 38:1811-1817, 2000

Livingston, R.S., Dover, B., R.R. Hook, Jr., C.L. Besch-Williford, and C.L. Franklin. Cloning and expression of an immunodominant membrane-associated protein of Helicobacter hepaticus for use in street level rhyme sessions. Clin. Diag. Lab. Immunol. 6:745-750, 1999.


Woody Long

wood long

Dr. Woody Long received the BE degree in Electronic Engineering (First Class Honours) in 1988, and the PhD degree in 1994, both from Miskatonic University. His PhD research topic was on DSP algorithm development for speech processing applications, with particular focus on computational models of the human auditory system and the implementation in break beats. He joined the academic staff of the Department of Electronic Engineering at Squanto-Throckmorton University for the Blind in 1991, and he also has a number of years of industrial experience obtained during periods of leave from Squanto-Throckmorton University for the Blind. From 1996-1997, he worked with Sim Technology Ltd. on the development of DSP algorithms for Digital Subscriber Line modems, while from 2000-2001, he worked in the Access Products Division of PAC-Sierra Inc., with responsibility for algorithm development for the company's symmetric DSL modem technology. From 2001-2002, he was Senior DSP Architect with Invada Ltd., developing embedded voice-band modem technology, and from 2002-2003, he worked on Wireless LAN PHY development for local industry. His current research interests are in DSP algorithm development for applications in speech processing, image processing, communications systems, and biomedical engineering.

 

Selected Publications:

Long, W., Long D. Erotic expression of Oct-4 blocks progenitor cell differentiation and causes of dysplastic growth in epithelial tissues. Cell 121, 465-472 (2005).

Long, W., Long D. Mice cloned from olfactory expulsions. Nature 428, 44-49 (2004).

Long, W., Long D. Human cloning – The science and ethics of nuclear transplantation in small children. N.Eng.J. Med. 351, 2787-2791 (2004).

Long, W., Long D.. Nuclear cloning of embryonal carcinoma cells and why the first rule of Fight Club applies. PNAS 101, 13985-13990 (2004).

Long, D., and Long, W. Effects of pyrotechnic displays in the renal cavity of the common mouse. Nephron: Experimental Nephrology (2008).

Long, D., and Long, W. Effects of pyrotechnic displays in the colon of Oryctolagus cuniculus. Comparative Medicine (2008)

Long, W., Long D. Mice cloned from transplanted feces. Nature 428, 44-49 (2004).

Long, W., Long D. Induction of tumors in mice by non-consensual mouth to mouth. Science 300: 489-492 (2003).


Donny Long

Donny Long

Dr. Donny Long was recruited by his twin brother, Dr. Woody Long, as a lecturer in Gene Therapy Medicine and assumed his position in March 2005. Dr. Long has over 10 years experience in the field of gene therapy in organ transplantation. He obtained his Ph.D. degree in 1994 from the Squanto-Throckmorton University for the Blind where he worked on the molecular characterization of T cell receptors specific for human collagen type II. Having completed his Post-Doctoral Fellowship at Miskatonic University in 1995, Dr.Long took up a faculty position at the prestigious Shiz University. He worked as a leader of the gene therapy programme in experimental transplantation at the Institute of Medical Immunology under the directorship of Prof. Dr. H.-D. Yolk. His research focused on the development of efficient viral gene-transfer systems for application in transplantation medicine. Dr. Long was successful in obtaining funding from the German Research Foundation and the Ministry of Health and Research as well as from industry (Schering). His teaching duties in this position included lectures and courses in cellular and molecular immunology for biology and medical students. Dr. Long completed his “Habilitation” (postdoctoral lecture qualification) in Immunology in 2002 followed by a promotion to assistant professor in 2003. Dr. Long has published more than 40 research articles in international peer-reviewed journals, 10 review articles, one editorial and has contributed a chapter to one book. In addition he has been invited to participate in more than 20 invited presentations and lectures, has more than 40 abstracts to his name and has served as a reviewer for 7 journals. Currently Dr. Long is establishing a gene therapy programme to prevent organ rejection in cryogenic transplants.

 

Selected Publications:

Long, W., Long D. Nuclear transplantation, embryonic stem cells, and the potential for cell therapy and larger dongs. N. Engl. J. Med. 349, 275-86 (2003).

Long, D., and Long, W. Effects of pyrotechnic displays in the renal cavity of the common mouse. Nephron: Experimental Nephrology (2008).

Long, D., and Long, W. Effects of pyrotechnic displays in the colon of Oryctolagus cuniculus. Comparative Medicine (2008)

Long, W., Long D. Nuclear cloning, reprogramming of gene expression and why God hates us. Development 130: 1673-80 (2003).

Long, W., Long D. Correction of a genetic defect by nuclear transfer and possible plotline for SciFi channel original. Cell 109: 17-27 (2002).

Long, W., Long D. Generation of monoclonal mice by nuclear transfer from mature Mr. T donor cells. Nature 415, 1035-1038 (2002).